Biography

Outlining the concise chronicles of my life: education, expertise, interests, obsessions and whereabouts.

• My complete Curriculum Vitae

• My Profile at Stanford University

• Publications on Google Scholar

• Publications on PubMed

• Copies of Publications

A great end to 2017! My SEM micrograph titled ‘Microscopic Escher’ won 1st Prize in the National SAASTA Science Lens competition. Category: Science as Art

 

I am also delighted that my ‘Biofilm Hand’ was awarded a first prize in the National Science Foundation’s International Visualization Challenge –  Illustration Category

Hot off the Press and in the Press:

2025

Dual Contrast-Enhanced Microcomputed Tomography Uncovers Leaflet-Dependent Patterns of Macrocalcification, Fibrous Extracellular Matrix Remodeling, and Adipocyte Degeneration in Calcific Aortic Stenosis. Journal of the American Heart AssociationEl Zeini, M., Tacco, I. R., Jimenez, J. I., Kabiri, A., Vailionis, A., Perrino, J., Burns, D., Jensen, K. C., Burdon, T. A., Shudo, Y., Woo, Y. J., Liang, T., Alexander, K. M., Joubert, L. M., Chen, I. Y.

Cryoprotectants-assisted plunge freezing of thick brain tissue specimens for targeted physiologically relevant cryo-imaging in situ. bioRxiv : the preprint server for biologyWeier, A., Perez, L., Gao, F., Morgan, E. T., Liu, P., Mounteer, I. C., Morgan, G. P., Shi, Q., Vigil, F. A., Joubert, L. M., Hoenger, A., Stowell, M. H., Klykov, O.2025

Cyanobacteria and Chloroflexota cooperate to structure light-responsive biofilms. Proceedings of the National Academy of Sciences of the United States of AmericaBunbury, F., Rivas, C., Calatrava, V., Malkovskiy, A. V., Joubert, L. M., Parvate, A. D., Evans, J. E., Grossman, A. R., Bhaya, D.2025; 122 (5): e2423574122

2024

Dramatic changes in mitochondrial subcellular location and morphology accompany activation of the CO2 concentrating mechanism. Proceedings of the National Academy of Sciences of the United States of AmericaFindinier, J., Joubert, L. M., Fakhimi, N., Schmid, M. F., Malkovskiy, A. V., Chiu, W., Burlacot, A., Grossman, A. R.2024; 121 (43): e2407548121

Visualizing spatial and temporal responses of plant cells to the environmentZaoralova, M., Azaldegui, C. A., Sica, A. V., Rui, Y., Joubert, L., Dinneny, J., Dahlberg, P. D.CELL PRESS. 2024: 420A

2023

Commensal protists in reptiles display flexible host range and adaptation to ectothermic hosts. mBioGerrick, E. R., DeSchepper, L. B., Mechler, C. M., Joubert, L. -., Dunker, F., Colston, T. J., Howitt, M. R.2023: e0227323

CryoET reveals organelle phenotypes in huntington disease patient iPSC-derived and mouse primary neurons. Nature communicationsWu, G. H., Smith-Geater, C., Galaz-Montoya, J. G., Gu, Y., Gupte, S. R., Aviner, R., Mitchell, P. G., Hsu, J., Miramontes, R., Wang, K. Q., Geller, N. R., Hou, C., Danita, C., Joubert, L. M., Schmid, M. F., Yeung, S., Frydman, J., Mobley, W., Wu, C., Thompson, L. M., Chiu, W.2023; 14 (1): 692

2022

Visualization of the distribution of covalently cross-linked hydrogels in CLARITY brain-polymer hybrids for different monomer concentrations. Scientific reportsMalkovskiy, A. V., Tom, A., Joubert, L., Bao, Z.2022; 12 (1): 13549

Interactions between mTORC2 core subunits Rictor and mSin1 dictate selective and context-dependent phosphorylation of substrate kinases SGK1 and Akt. The Journal of biological chemistryYu, Z., Chen, J., Takagi, E., Wang, F., Saha, B., Liu, X., Joubert, L. M., Gleason, C. E., Jin, M., Li, C., Nowotny, C., Agard, D., Cheng, Y., Pearce, D.2022: 102288

Correlative Light and Electron Microscopy (CLEM): Bringing Together the Best of Both Worlds to Study Neuronal Autophagy Imaging and Quantifying Neuronal AutophagyKriel, J., Joubert, L.

2021

Kuehlmann, B., Zucal, I., Bonham, C.A. et al. SEM and TEM for identification of capsular fibrosis and cellular behavior around breast implants – a descriptive analysis. BMC Mol and Cell Biol 22, 25 (2021). https://doi.org/10.1186/s12860-021-00364-8

Kriel, J., Lumkwane, D., Joubert, L-M, et al. 2021. Correlative Light and Electron Microscopy (CLEM): Bringing together the best of both worlds to study neuronal autophagy. Springer Nature Experiments: 3

PCA Consortium et al. 2021. Science Forum: Vistion, challenges and opportunities for a Plant Cell Atlas. eLife 2021;10:e66877 doi: 10.7554/eLife.66877

Zimanyi, C. et al. 2021. Cross-training to shared standards at the national cryoEM cdnters using ‘Merit Badges’. Microscopy and Microanalysis meeting Aug. 1-5.

2020

Liu J, Kim y , Richardson C, Tom A, et al. 2020. Genetically targeted chemical assembly of functional materials in living cells, tissues, and animals. Science 367: 1372-1376. DOI: 10.1126/science.aay4866

Shudo, Y, MacArthur W, Kunitomi, Y, Joubert L-M et al. 2020. Three-Dimensional Multilayered Microstructure using Laser Diret-Writing System. Tissue Engineering Part A https://doi.org/10.1089/ten.TEA.2019.0313

Edwin Chang, Chirag Patel, Caroline J. Young, Thomas Anthony Flores, Lydia-Marie Joubert, Yitian Zeng, Robert Sinclair and Sanjiv Gambhir
Abstract 6258: Combining the glioblastoma cell membrane-permeabilizing effect of tumor treating fields with chemotherapy. Proceedings: AACR Annual Meeting 2020; April 27-28, 2020 and June 22-24, 2020; Philadelphia, PA. DOI: 10.1158/1538-7445. AM2020-6258 Published August 2020.

2019

Prigozhin MB, Maurer PC, et al. 2019. Bright sub-20-nm cathodoluminescent nanoprobes for electron microscopy. Nature Nanotechnology Nature Nanotechnology (2019) DOI: 10.1038/s41565-019-0395-0

Reichhardt C, Joubert L-M, Clemons K, Stevens DA, Cegelski L. 2019. Integration of electron microscopy and solid-state NMR analysis for new views and compositional parameters of A. fumigatus biofilms. Medical Mycology 27: S239 – S244. https://doi.org/10.1093/mmy/myy140

Tamuhle, T., Joubert, L-M., Willemse, D., Williams, M. 2019. SufT is required for growth of Mycobacterium smegmatis under iron limiting conditions. Microbiology 166(3) https://doi.org/10.1099/mic.0.000881

Alawode, A., Amaindamhen, S., Joubert, L-M., et al. 2019. Performance evaluation of a natural based adhesive derived from Irvingia wood species kernel extracts on wood panel production.  Journal of Adhesion Science and Technology 34(9):995-1012 DOI 10.1080/01694243.2019.1689720

Woodburn, K., Clemens, L., et al. 2019. Designed Antimicrobial Peptides for Recurrent Vulvovaginal Candidiasis Treatment. Antimicrobial Agents and Chemotherapy 63(11). DOI: 10.1128/AAC.02690-18

Sakie, S. ,Trollope, K.M., Joubert, L-M, et al. 2019. The antifungal and Cryptococcus neoformans virulence attenuating activity of Pelargonium sidoides extracts. Jnl of Ethnopharmacology, 235: 122-132. https://doi.org/10.1016/j.jep.2019.02.008

2018

Chang E, Patel CB, Pohling C. et al. 2018. Tumor treating fields increases membrane permeability in glioblastoma cells. Cell Death Discovery 4:113-127. https://doi.org/10.1038/s41420-018-0130-x

Liu G, Zhang Y, Peng C, Yang T, Joubert, L-M, Chu, S. 2018. Single upconversion nanoparticle imaging at sub-10 W cm-2 irradiance. Nature Photonics 12: 548–553 https://doi.org/10.1038/s41566-018-0217-1

Prighozin MB, Maurer PC, Courtis AM, et al. 2018. Bright sub-20 nm cathodoluminescent nanoprobes for multicolor electron microscopy https://arxiv.org/abs/1806.00075

SoRelle ED, Yecies DW, Liba O, et al. 2018. Wide-field dynamic monitoring of immune cell trafficking in murine models of glioblastoma.  https://www.biorxiv.org/content/early/2017/11/17/220954

Tajerian M, Hung V, Nguyen H, Lee G, Joubert L-M et al. 2018. The Hippocampal Extracellular Matrix Regulates Pain and Memory After Injury. Molecular Psychiatry https://doi.org/10.1038/s41380-018-0209-z.

Tsai, JM., Sinha, R., Seita, J., Fernhoff, N… Joubert, L-M. et al. 2018. Adhesions are derived from hypoxia responsive MSLN+ mesothelium and are resolved via targeted therapies. Science Translational Medicine 10 (469): eaan6735.  https://doi.org/10.1126/scitranslmed.aan6735

2017

Li, Y. et al. 2017. Atomic structure of sensitive battery materials and interfaces revealed by cryo–electron microscopy. Science 358, Issue 6362, pp. 506-510 DOI: 10.1126/science.aam6014

Margulis K, Zhang X, Joubert L-M, Bruening K, Christopher J. 2017. Formation of Polymeric Nanocubes by self-assembly of crystallization of ditiolane-containing triblock copolymers. Angew Chem. 56(51): 16357-16362 doi: 10.1002/anie.201709564.

Santoro F., Zhao W., Joubert L-M, et al. Revealing the Cell-Material interface with nanometer resolution by focused Ion Beam/Scanning Electron Microsocopy. ACS Nano 2017 Aug 22:11(8): 8320-8328. 10.1021/acsnano.7b03494

Nazik, H, Joubert, L-M, et al. 2017. Pseudomonas-phage inhibition of Candida albicans. Microbiology doi: 10.1099/mic.0.000539

Kim J.J. et al. 2017. Microfibrous Scaffolds Enhance Endothelial Differentiation and Organization of Induced Pluripotent Stem Cells. Cellular and Molecular Bioengineering 10(5). Aug 2017 DOI: 10.1007/s12195-017-0502-y

Joubert LM. 2017. Variable Pressure-SEM: a versatile tool for visualization of hydrated and non-conductive specimens. In: Microscopy and Imaging Science: practical approaches to applied research and education. Formatex Research Center.

Long C, Galvez MG, Legrand A, Joubert LM et al. 2017. Intratendinous Injection of Hydrogel for Reseeding Decellularized Human Flexor Tendons. Plastic and Reconstructive Surgery, 139(6):1305e–1314e, JUN 2017 DOI: 10.1097/PRS.0000000000003359

2016

Hayer A, Shao L, Chung M, Joubert LM, Yang HW, Tsai FC, Bisaria A, Betzig E, Meyer T. 2016. Engulfed cadherin fingers are polarized junctional structures between collectively migrating endothelial cells. Nat Cell Biol. 18(12): 1311-1323.

Joubert LM, Fereira JA, Stevens DA, Nazik H, Cegelski L. 2016. Visualization of Aspergillus fumigatus biofilms with Scanning Electron Microscopy and Variable Pressure-Scanning Electron Microscopy: A comparison of processing techniques. J Microbiol Methods 132: 46-55. doi: 10.1016/j.mimet.2016.11.002

Penner JC, Ferreira JA, Secor PR, Sweere JM, Birukova MK, Joubert LM, Haagensen JA, Garcia O, Maklovskiy AV, Kaber G, Nazik H, Manasherob R, Spormann AM, Clemons KV, Steven DA, Bollyky PL. 2016. Pf4 bacteriophage produced by Pseudomanas aeruginosa inhinits Aspergilus fumigatus metabolsim via iron sequestration. Microbiology 162(9):1583-1594. doi: 10.1099/mic.0.000344.

Yasuhiro Shudo, Jeffrey E. Cohen, Andrew B. Goldstone, John W. MacArthur, Jay Patel, Bryan B. Edwards, Michael S. Hopkins, Amanda N. Steele, Lydia-Marie Joubert, Shigeru Miyagawa, Yoshiki Sawa, Y. Joseph Woo. 2016. Isolation and trans-differentiation of mesenchymal stromal cells into smooth muscle cells: Utility and applicability for cell-sheet engineering.Cytotherapy 18(4):510-517 FRONT COVER IMAGE

2015

Reichhardt, C, Ferreira, JAG, Joubert, L-M, Clemons,KV,  Stevens, DA  Cegelski, L. 2015. Anaysis of the Aspergillus fumigatus Extracellular Matrix by Solid-State Nuclear Magnetic Resonance Spectroscopy. Eukaryotic Cell 10 July 2015, doi: 10.1128/EC.00050-15 FRONT COVER IMAGE

Nakayama KH, Joshi PA, Lai ES, Gujar P, Joubert L-M, Chen B, Huang NF. Bi-layered vascular graft derived from human induced pluripotent stem cells with biomimetic structure and function. Regen Med 2015

2014

Ronaghi M, Nasr M,  Ealy, Durruthy-Durruthy R, Waldhaus J, Diaz G H., Joubert L-M, Oshima K and Heller S. Stem Cells and Development.  Inner ear Hair-Like cells form Human Embryonic Stem cells doi:10.1089/scd.2014.0033.

2013

Farnebo, S, CY Woon, T Schmitt,  L-M Joubert, M Kim, H Pham, J Chang. 2013. Design and characterization of an injectable tendon hydrogel: a novel caffold for guided tissue regeneration in the muscoskeletal system. Tissue Engineering PartA

Jiang X, AV Malkovskiy, W Tian, YK Sung, W Sun, JL Hsu, S Manickam, D Wagh, L-M Joubert, G Smemnza, J Rajadas, MR Nicolls. 2013. Promotion of airway anastomotic microvascular regeneration and allevition of airway ischemia by deferoxamine nanoparticles. Biomaterials 10/2013

Joubert, Lydia-Marie. 2013. VP-SEM: Unsung Hero of SEM imaging. Imaging and Microscopy 1/2013 (invited)

Joubert, Lydia-Marie. 2013. High Resolution Imaging with Field Emission SEM: the need for downstream plasma-cleaning in biological applications. Microscopy and Analysis, May 2013 (invited)

2012

Galic M, Jeong S, Tsai FC, Joubert LM, Wu YI, Hahn KM, Cui Y, Meyer T. 2012. External push and internal pull forces recruit curvature-sensing N-BAR domain protein to the plasma membrane. Nature Cell Biol. 14(8).doi: 10.1038/ncb2533. Epub 2012 Jul 1.

Reichelt M, Joubert L, Perrino J, Koh AL, Phanwar I, et al. (2012) 3D Reconstruction of VZV Infected Cell Nuclei and PML Nuclear Cages by Serial Section Array Scanning Electron Microscopy and Electron Tomography. PLoS Pathog 8(6): e1002740. doi:10.1371/journal.ppat.1002740

2011

Gaume, Romain and Lydia-Marie Joubert. 2011. Airtight container for the transfer of atmosphere-sensitive material into vacuum-operated characterization instruments. Review of Scientific Instruments 82 (2011) 123705

Howitt, M, J Lee, P Lertsethtakarn, R Vogelman, L-M Joubert, K Ottemann, and M Amieva. 2011. ChePep controls Helicobacter pylori infection of the gastric glands and chemotaxis in the Epsilonproteobacteria. mBio Aug 2011. doi:10.1128/mBio.00098-11,

McCartt, A; Gates, S; Jeffries, J; Hanson, R; Joubert, L; Buhr, T. 2011. Response of Bacillus thuringiensis Al Hakam endospores to gas dynamic heating in a shock tube. Zeitschrift fur Physikalische Chemie 225:1367-1377

Neofytou, E.A., Chang, E., Patlola, B., Joubert, LM, et al. 2011. Adipose tissue-derived stem cells display a proangiogenic phenotype on 3D scaffolds. Jnl Biomedical Materials Res Part A, Vol98A, 3:383-393

Peng, K, Broz, P, Jones, J, Joubert, LM, Monack, D. 2011. Elevated AIM2-mediated pyroptosis triggered by hypercytotoxic Francisella mutant strains is attributed to increased intracellular bacteriolysis. Cellular Microbiology 13(10): 1586-1600